3-mercaptopyruvate

3-mer·cap·to·py·ru·vate

(mer-kap'tō-pī-rū'vāt),
The transaminated product of cysteine; formed in cysteine catabolism; elevated in people with a deficiency of 3-mercaptopyruvate sulfurtransferase.
References in periodicals archive ?
The formation of endogenous H[sub]2S needs cysteine as substrate, and mainly involves three enzymes: cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (MPST).
3-mercaptopyruvate sulfur transferase occurs in cytoplasm and mitochondria (cytoplasm > mitochondria), while rhodanese is located only in mitochondria (Nagahara et al.
To this end, we found that cells expressing 3-mercaptopyruvate sulfurtransferase (3MST) and cysteine aminotransferase (CAT) contain increased levels of bound sulfane sulfur.
2]S) is an endogenous gaseous signaling molecule in mammalian tissues, which is enzymatically synthesized by cystathionine [beta]-synthase (CBS), cystathionine y-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (3-MST) [17-19].
2]S in the human body is catalyzed by several enzymes, including two pyridoxal-5'-phosphate- (PLP-) dependent enzymes, namely, cystathionine-[beta]-synthase (CBS) and cystathionine-[gamma]-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (MST) [4].
Other enzymes such as 3-mercaptopyruvate sulfurtransferase (MST) and cysteine aminotransferase (CAT) are also important in specific tissue types [12].
2]S-generating enzymes cystathionine-[beta]-synthase (CBS), cystathionine-[gamma]-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (3MST) and metabolize cysteine [15].
Recently, 3-mercaptopyruvate sulfurtransferase (3-MST) was reported as the third enzyme for [H.
2]S-producing enzyme, 3-mercaptopyruvate sulfurtransferase (3-MST), has recently been discovered; this enzyme generates [H.
2]S) is a gasotransmitter generated endogenously by cystathionine-[gamma]-lyase (CSE), cystathionine-[beta]-synthase (CBS), and 3-mercaptopyruvate sulfurtransferase (3-MST).
Recently, it was found that another mitochondrial enzyme, 3-mercaptopyruvate sulfurtransferase (3-MST) in conjunction with cysteine aminotransferase (CAT), contributes significantly in generating [H.