dopamine

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dopamine

 [do´pah-mēn]
a compound produced by the decarboxylation of dopa; it is the direct precursor in the synthesis of norepinephrine and is also a neurotransmitter in the central nervous system. It is administered intravenously to correct hemodynamic imbalance in persons with shock because it increases blood pressure, especially systolic pressure, as well as urinary output; it is also used as a cardiac stimulant.

do·pa·mine (DM),

(dō'pă-mēn),
An intermediate in tyrosine metabolism and precursor of norepinephrine and epinephrine; neurotransmitter is the peripheral and central nervous systems; depletion of dopamine produces Parkinson disease.

dopamine

/do·pa·mine/ (-mēn) a catecholamine formed in the body by the decarboxylation of dopa; it is an intermediate product in the synthesis of norepinephrine, and acts as a neurotransmitter in the central nervous system. The hydrochloride salt is used to correct hemodynamic balance in the treatment of shock and is also used as a cardiac stimulant.

dopamine

(dō′pə-mēn′)
n.
A monoamine neurotransmitter formed in the brain by the decarboxylation of dopa and essential to the normal functioning of the central nervous system. A reduction in its concentration within the brain is associated with Parkinson's disease.

dopamine

[dō′pəmin]
a naturally occurring sympathetic nervous system neurotransmitter that is the precursor of norepinephrine. It is produced in the substantia nigra and transmitted to the putamen and caudate nucleus. It has an inhibitory effect on movement. A depletion of dopamine produces the symptoms of rigidity, tremors, and bradykinesia that are characteristic of Parkinson's disease. It is available as an intravenously injectable drug. Dopamine has potent dopaminergic, beta-adrenergic, and alpha-adrenergic receptor activity. See also dopamine hydrochloride.

dopamine

Neurology A catecholamine hormone and neurotransmitter essential to CNS activity; it is involved motor control, cognition, and reward; abnormal dopamine levels occur in Parkinson's disease, paranoia, memory and concentration defects; dopamine may modulate endorphin levels, altering perception of pain and pleasure; it restricts prolactin, affecting libido See Biogenic amine, Catecholamine, Indolamine, Serotonin.

do·pa·mine

(DM) (dō'pă-mēn)
An intermediate in tyrosine metabolism and precursor of norepinephrine and epinephrine.

dopamine

A monoamine NEUROTRANSMITTER and hormone with an adrenaline-like action. Dopamine is the principal neurotransmitter in the extrapyramidal system. It is formed in the brain from the amino acid tyrosine via dopa and the latter, in the form of levodopa is used to treat PARKINSON'S DISEASE. Dopamine is the precursor of noradrenaline. It is also concerned with mood, memory and food intake. Excess is associated with psychiatric disorders. Dopamine is converted into at least 30 other substances some of which are hallucinogenic. The drug is on the WHO official list.

dopamine

the decarboxylation product of DOPA. Formula: C8H11 O2 N.

Dopamine

A neurochemical made in the brain that is involved in many brain activities, including movement and emotion.

dopamine (dōˑ·p·mēn),

n a neurochemical that supports fine motor activity, blood pressure, focus, inspiration, intuition, enthusiasm, and joy, among other functions.

do·pa·mine

(dō'pă-mēn)
An intermediate in tyrosine metabolism and precursor of norepinephrine and epinephrine.

dopamine

a compound, hydroxytyramine, produced by the decarboxylation of dopa; an intermediate product in the synthesis of norepinephrine. It is a neurotransmitter in the central nervous system; administered intravenously to correct hemodynamic imbalance in shock syndrome.

dopamine agonist
used to terminate pregnancy. See bromocriptine, cabergoline.
dopamine β-hydroxylase
enzyme catalyzing the synthesis of norepinephrine from dopamine. A copper-containing mono-oxygenase requiring vitamin C (ascorbic acid).