3-hydroxyglutaric acid
3-hy·drox·y·glu·tar·ic ac·id
(hī-drok'sē-glū-tar'ik as'id),A dicarboxylic acid that accumulates in people with glutaric acidemia type I.
References in periodicals archive
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Biochemically, GA-1 is characterized by marked increase of glutaric acid (GA), 3-hydroxyglutaric acid (3-OH-GA) in urine, plasma and cerebrospinal fluid which is detected by gas chromatography/mass spectrometry (GC/MS).
Sensitivity and specificity of free and total glutaric acid and 3-hydroxyglutaric acid measurements by stable-isotope dilution assays for the diagnosis of glutaric aciduria type I.
Diagnosis is made on the basis of increased glutaric and 3-hydroxyglutaric acids in urine (10).
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