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β-hy·drox·y-β-meth·yl·glu·tar·yl-CoA (HMG-CoA),

A key intermediate in the synthesis of ketone bodies, of steroids, and of farnesyl and geranyl derivatives.
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e) ASA, argininosuccinic aciduria; C12, dodecanoylcarnitine; C18:10H, hydroxyoctadecenoylcarnitine; C180H, hydroxyoctadecanoylcarnitine; IVA, isovaleric acidemia; 3-MCC, 3-methylcrotonyl-CoA carboxylase; HMG, 3-hydroxy-3-methylglutaryl-CoA lyase.
A second cDNA clone, 3-hydroxy-3-methylglutaryl-CoA reducrase, appeared to be slightly downregulated in the ES-treated fish compared with all the other exposure groups and controls.
3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency(*)--If this disorder is untreated, it is likely to result in death during childhood.
Adzuki resistant starch lowered serum cholesterol and hepatic 3-hydroxy-3-methylglutaryl-CoA mRNA levels and increased hepatic LDL-receptor and cholesterol 7alpha-hydroxylase mRNA levels in rats fed a cholesterol diet.