(redirected from 20-methylcholanthrene)


A highly carcinogenic hydrocarbon that can be formed chemically from deoxycholic or cholic acids, or from cholesterol; it induces the synthesis of cytochrome P-450 mRNA; the choice between 3- or 20- for the methyl group depends upon whether hydrocarbon (inner) or steroid (outer) numbering is chosen; in the latter case, the formal relationship to the cholic acids and cholesterol is clear.
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They also found that intraperitoneal injections of NSE significantly reduced the incidence of sarcoma development after 30 days of subcutaneous 20-methylcholanthrene (MCA) injections.
The in vivo and in vitro inhibitory effects of TQ against 20-methylcholanthrene (MC)-induced fibrosarcoma (Badary and Gamal, 2001) and against benzo[a]pyrene-induced forestomach carcinogenesis (Badary et al.
Development of hepatomas in inbred albino mice following treatment with 20-methylcholanthrene.