A rare component of transfer RNAs; a thioamide derivative that inhibits the synthesis of thyroid hormones; hence, a goitrogen; similar to propylthiouracil.
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Interactions of 5-fluorouracil (5-FU), a commercially available anti-cancer drug and two other possibly anti-cancer actives, 2-thiouracil (2-TU) and 2,4-dithiouracil (DTU), with anionic sodium dodecyl sulphate (SDS) and cationic cetlytrimethyl ammonium bromide (CTAB) surfactants were studied using cyclic voltammetry and UV-Visible spectroscopic techniques.
2-thiouracil (2-TU) and 2,4- dithiouracil (DTU) are known as effective neoplastigen, tumorigen, carcinogen and teratogen agents.
High purity (=99%) chemicals 2-Thiouracil (2-TU), 2,4-dithiouracil (DTU), 5-fluorouracil (5-FU), sodiumdodecylsulphate (SDS), and cetyltrimethylammonium bromide (CTAB), were purchased from Sigma and were used as received without any further purification.