(TNT), a relatively water soluble nitroaromatic compound, is a common pollutant in soil and groundwater at sites with substantial military activities, such as those associated with munition production, handling, testing, and disposal of explosive and propellent materials.
Metabolism of 2,4,6-trinitrotoluene by Pseudomonas sp.
Effect of 2,4,6-trinitrotoluene on soil bacterial communities, Journal of Industrial Microbiology and Biotechnology 35: 225-236.
Effects and bioavailability of 2,4,6-trinitrotoluene in spiked and field-contaminated soils to indigenous microorganisms, Environmental Toxicology and Chemistry 18: 2681 -2688.
This could be either the explosive component, which is most commonly 2,4,6-trinitrotoluene
(TNT), or one of the byproducts from its manufacture.
The goals of this project are: (1) to determine the acute toxicity of 2,4,6-trinitrotoluene (TNT) using the trypan blue dye exclusion and lactate dehydrogenase (LDH) assays; (2) to determine the cellular response mechanism of TNT in human hepatic carcinoma cell (HepG2) lines; and (3) to assess the genotoxic effects of TNT in HepG2 cells.
INDUCTION PROFILE AND CELLULAR RESPONSE MECHANISMS OF HUMAN LIVER CARCINOMA CELL (HEPG2) LINE TREATED WITH ARSENIC TRIOXIDE, CADMIUM CHLORIDE, AND 2,4,6-TRINITROTOLUENE
During 1994, a UV/oxidation system was installed at the Milan Army Ammunition Plant (Milan, TN, USA) to treat holding ponds contaminated with explosive compounds (2,4,6-trinitrotoluene
, 2,4- and 2,6-dinitrotoluenes, nitrobenzene, etc.) .
Ramos, "Biological degradation of 2,4,6-trinitrotoluene
," Microbiology and Molecular Biology Reviews, vol.
Ecotoxicological evaluation of in situ bioremediation of soils contaminated by the explosive 2,4,6-trinitrotoluene
Vitamins added to soil increased the rate of degradation of 2,4,6-trinitrotoluene (TNT) .
Limane et al., "The role of nutrients in the biodegradation of 2,4,6-trinitrotoluene in liquid and soil," Journal of Environmental Management, vol.