dioxin

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dioxin

 [di-ok´sin]
a highly toxic and teratogenic chlorinated hydrocarbon that is a trace contaminant in the herbicides2,4,5-T and agent orange.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

di·ox·in

(dī-oks'in),
1. A ring consisting of two oxygen atoms, four CH groups, and two double bonds; the positions of the oxygen atoms are specified by prefixes, as in 1,4-dioxin.
2. Abbreviation for dibenzo[b,e][1,4]dioxin which may be visualized as an anhydride of two molecules of 1,2-benzenediol (pyrocatechol), thus forming two oxygen bridges between two benzene moieties, or as a 1,4-dioxin with a benzene ring fused to catch each of the two CH=CH groups.
3. A contaminant in the herbicide, 2,4,5-T; it is potentially toxic, teratogenic, and carcinogenic.
Farlex Partner Medical Dictionary © Farlex 2012

dioxin

(dī-ŏk′sĭn)
n.
Any of several carcinogenic, mutagenic, and teratogenic polychlorinated heterocyclic aromatic hydrocarbons that can occur as impurities in petroleum-derived herbicides and as byproducts of manufacturing chemicals and burning fuels and waste.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Any of a family of highly toxic chlorinated hydrocarbons in which 2 benzene rings are linked by 2 O2 atoms, which includes dibenzodioxins and dibenzofurans
Lab Increased PT, increased lipid levels
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

dioxin

Toxicology Any of a family of highly toxic chlorinated hydrocarbons Clinical In humans, intense chronic exposure causes weight loss, myalgias, insomnia, dyspnea, cold intolerance, irritability, peripheral neuropathy, hepatomegaly, hemorrhagic cystitis, chloracne, actinic elastosis, loss of libido, impotence Lab ↑ PT, ↑ lipid levels. See Agent Orange, Times Beach.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

di·ox·in

(dī-ok'sin, dī-ok'sin)
1. A ring consisting of two oxygen atoms, four CH groups, and two double bonds; the positions of the oxygen atoms are specified by prefixes, as in 1,4-dioxin.
2. A contaminant in the herbicide, 2,4,5-T; its potential toxicity, carcinogenicity, and teratogenicity are controversial.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

dioxin

a chemical byproduct of the manufacture of certain herbicides and bactericides, particularly tetrachlorodibenzo-paradioxin (TCDD), which is extremely toxic.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Dioxin

A toxic chemical found in weed killers that has been linked to the development of endometriosis.
Mentioned in: Endometriosis
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Retinoic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin selectively enhance teratogenesis in C57BL/6N mice.
Identification of the aryl hydrocarbon receptor target gene TiPARP as a mediator of suppression of hepatic gluconeogenesis by 2,3,7,8-tetrachlorodibenzo-p-dioxin and of nicotinamide as a corrective agent for this effect.
Impairment of thymus-dependent immune functions by exposure of the developing immune system to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
2,3,7,8-tetrachlorodibenzo-p-dioxin selectively enhances spontaneous IgE production in B cells from atopic patients.
Accidental release of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) at Seveso, Italy.
OBJECTIVES: We investigated the action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on acetylcholinesterase (AChE), a key enzyme in cholinergic neurotransmission.
The relevance of fat content in toxicity of lipophilic chemicals to terrestrial animals with special reference to dieldrin and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
BACKGROUND: Exposure reconstructions and risk assessments for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other dioxins rely on estimates of elimination rates.
Different rat strains have lethal doses (median lethal dose, at 50%; [LD.sub.50]) of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) that vary by a factor of 1,000 (Pohjanvirta et al.
Polychlorinated dibenzodioxins (PCDDs), dibenzofurans (PCDFs), and biphenyls (PCBs) constitute a group of widespread and persistent organic pollutants with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) being the most toxic member of this group (Birnbaum 1994b, 1995a, 1995b).

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