SLC45A2

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SLC45A2

A gene on chromosome 5p13.2 that encodes solute carrier family 45, member 2, which is a melanocyte differentiation antigen thought to transport substances required for melanin biosynthesis. It is expressed in most melanoma cell lines and melanocytes.

Molecular pathology
SLC45A2 mutation causes oculocutaneous albinism type 4.
References in periodicals archive ?
This snap shows John and his school pals from Class 1A1 - and he's been able to name almost everyone.
The authors report that cytochrome P450 1A1 (CYP1A1) expression is highest in whales from the Galapagos Islands and lowest in sampling sites farthest away from continents.
Several diagnostic products, including Roche's Amplichip CYP450 and Third Wave's Invader UGT 1A1 assay, have been approved by FDA for determining whether a drug treatment will be sate for an individual patient, but there have been few instances of a sponsor pursuing clinical development of a drag and diagnostic in tandem.
Suite 420, Vancouver, BC V5Z 1A1, tel: 604-687-3223, fax: 604-687-3277, email: admin@worldpeaceforum.
Sioux Lookout, P8T 1A1 1(800) 465-3844 2,000 square ft.
Among the proposed explanations for this inflammation are an immunologic reaction against collagen, mutations of collagen gene 1A1, and a viral infection.
The Rannugs note that shining light on skin cells grown in the test tube also increases the activity of CYP 1A1.
In humans, cytochrome P450 1A1 induction in response to cigarette smoke in vivo has been noted in extrahepatic tissue, including placenta [5-7]; while cigarette smoke predisposition of lymphocytes to in vitro induction of AHH by a follow-up hydrocarbon inducer such as benzanthracene has also been suggested [8].
Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin.
For Group 1, classes 1A1, 1A2, 1A3, 1AIO and 1A7 are initial exchangeable certificates.
Credit Enhancement for the 1A1 certificate is provided by the structural support of the underlying transaction and by the 13.
NEW YORK -- Fitch Ratings has revised the recovery ratings on classes 1A1, 1A2, 2A1, 2A2, 3A1, 3A2, and 4A1 of Mortgage Asset Securitization Transactions, Inc.