YWHAZ

(redirected from 14-3-3 zeta)

YWHAZ

A gene on chromosome 8q23.1 that encodes an adapter protein which regulates a broad spectrum of general and specialised signalling pathways by binding to a large number of partners, usually by recognising a phosphoserine or phosphothreonine motif.
References in periodicals archive ?
Roth, "Identification of cofilin and LIM-domain-containing protein kinase 1 as novel interaction partners of 14-3-3 zeta," The Biochemical Journal, vol.
JQ284433) encodes 176 amino acid residues and contains the conserved structure of 14-3-3 zeta proteins.
Comparison of Pc-14-3-3 in overall sequence with 14-3-3 zeta proteins from Caenorhabditis elegans,
Comparisons of similarity in full-length amino acid sequence between 14-3-3 zeta proteins are shown in the lower corner.
clarkii and analysis of deduced amino acid sequence shows that the Pc-14-3-3 is a member of 14-3-3 zeta isoforms (Yaffe and Elia, 2001).
Among these isoforms, 14-3-3 zeta had been confirmed to be involved in the response to salinity stress (Kaeodee et al., 2011; Shu et al., 2012) and virus infection (Chongsatja et al., 2007; Wang et al., 2007).