13-cis-retinoic acid


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13-cis-ret·i·no·ic ac·id

the retinoid most used in the U.S. to treat acne; it works by reducing sebum secretion. Use in pregnancy is contraindicated because of teratogenicity.
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Beta carotene and 13-cis-retinoic acid both belong to a family of compounds known as the retinoids.
Depression-a side effect of 13-cis-retinoic acid therapy.
The adjuvant administration of 13-cis-retinoic acid produced a statistically significant (p = 0.002) inhibitory effect on the tamoxifen induced increase in the area of endometrium, whereas no significant suppressive effect of this drug has been observed on the other parameters when compared with Group B.
Oral isotretinoin (13-cis-retinoic acid) therapy in severe acne: Drug and vitamin A concentrations in sebum and skin.
Effects of 13-cis-retinoic acid, all-trans-retinoic acid, and acitretin on the proliferation, lipid synthesis and keratin expression of cultured human sebocytes in vitro.
The adjuvant administration of 13-cis-retinoic acid showed a suppressive effect only on glandular epithelial height, when compared with Group B (p=0.01).
It is approved in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA) in patients who achieve at least a partial response to prior first-line multiagent, multimodality therapy.
The mother, from Stocksfield, Northumberland, remembered desperately trying to squeeze every drop from Joe's 13-cis-retinoic acid capsules for the six months he took the drug.
From the 1980s it was found that treating acne orally with 13-cis-retinoic acid (isotretinoin) during certain stages of pregnancy was dangerous, potentially causing cleft palate, heart defects, a disordered central nervous system and missing ears.
According to the company, Unituxin (dinutuximab) is a disialoganglioside, GD2-binding chimeric monoclonal antibody (ch14.18) indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2) and 13-cis-retinoic acid (RA) for pediatric patients with high-risk neuroblastoma.
not involving RAR and RXR), as well as the reported effect of 13-cis-retinoic acid on spatial memory learning.