11-desoxycorticosterone

11-desoxycorticosterone, deoxycorticosterone, deoxycortone

one of the mineralocorticoids, adrenocortical steroids which lack a substituent at C-11; has a greater effect on electrolyte metabolism than glucocorticoids. Available pharmaceutically as the acetate (DOCA), which is short-acting, and the pivalate (DOCP), a slow release form for use in the treatment of hypoadrenocorticism.
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2]/ day was started to decrease the stimulus of ACTH and curb the production of 11-desoxycorticosterone acetate (DOCA), seeking to control the patient's BP.
One of the enzymes affected is 11-beta-hydroxylase , which is responsible for the conversion of 11-desoxycorticosterone to corticosterone (both hormones possessing mineralocorticoid activity and being precursors to aldosterone) and 11-deoxycortisol to cortisol (10).