naphthol

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naphthol

 [naf´thol]
a phenol occurring in coal tar in two forms: α- or 1-naphthol and β- or 2-naphthol. It is used in dyes, insecticides, and pharmaceutical compounds. If excessive amounts are ingested, poisoning may result, characterized by anemia, jaundice, convulsions, and coma.

naph·thol

(naf'thol),
A hydroxynaphthalene, occurring in two forms: α-naphthol, a dye intermediate used in cytochemistry for l-arginine localization; and β-naphthol, also known as isonaphthol, used as an anthelmintic and antiseptic. Both forms are also used in the manufacture of dyes, organic chemicals, and rubber products.
Synonym(s): naphthalenol

naphthol

Toxicology A white crystalline phenol derivative intermediate in the synthesis of multiple compounds including pharmaceuticals Toxicity Abdominal pain, glomerulonephritis, convulsions, circulatory collapse, skin pigmentation
References in periodicals archive ?
Carbaryl, 1-naphthol and 2-naphthol inhibit the beta-1 thyroid hormone receptor-mediated transcription in vitro.
The region of the oxidation current of 1-naphthol as an AP enzymatic reaction product was observed at a potential between +100 and +400 mV (shown in Figure 2 as a red arrow for peaks curves 1 and 2) for different buffer solutions.
The chromatograms of the degradation products of Escherichia coli DH5[+ or -] at 285 and 315 nm are shown in figure 4 and 5, they were used for comparison with 1-naphthol chromatograms.
Figure 2 presents the cumulative distributions of urinary 1-naphthol to 2-naphthol ratios in the CHAMACOS cohort and NHANES.
Correlation of environmental carbaryl measurements with serum and urinary 1-naphthol measurements in a farmer applicator and his family.
1997 Urinary 1-naphthol excretion in the assessment of exposure to creosote in an impregnation facility.
Briefly, 2 mL urine was brought to room temperature and 50 [micro]L of a hexane solution containing 1 [micro]g/mL of [[sup.2][H.sub.7]] 1-naphthol (internal standard) was added.
(b) Percent > LOD (a) Missouri Minnesota p-Value (c) More often > LOD in Missouri than Minnesota subjects Alachlor mercapturate 92 25 < 0.0001 IMPY 96 58 0.001 Atrazine mercapturate 38 6 0.004 Metolachlor mercapturate 0 39 < 0.0001 2,4-D 12 0 0.059 More often > LOD in Minnesota than Missouri subjects 3,5,6-Trichloropyridinol 50 86 0.004 1-Naphthol 38 64 0.065 4-Nitrophenol 0 19 0.035 Similar no.
We assayed UDP-glucuronosyltransferase activities toward various substrates in the liver microsomes, which were activated by 0.01% cholate, in 200 [micro]L of 50 mM Tris-HCl buffer (pH 7.4), 0.5 mM Mg[Cl.sub.2] containing 0.25 mM substrate (testosterone, estradiol, BPA, or 1-naphthol) at 37 [degrees] C.
This study measured four specific urinary metabolites: 1-naphthol (1-NAP), atrazine metcapturate (AM), malathion dicarboxylic acid (MDA), and 3,5,6-trichloro-2-pyridinol (TCPy).