IFITM3

(redirected from 1-8U)

IFITM3

A gene on chromosome 11p15.5 that encodes an interferon-induced protein, which mediates innate cellular immunity against viral pathogens—e.g., influenza A H1N1, West Nile, and dengue viruses—by inhibiting the early steps of viral replication.
 
Molecular pathology
IFITM3 mutations are linked to increased susceptibility to viral infections.
References in periodicals archive ?
(2011) reported MIC against MRSA 3.56u l/ml and range 1-8u l/ml which exactly matches to the findings in the present study.
In patients with UC-associated cancer and a group of UC patients with chronic severe inflammation, the IFN-inducible gene family 1-8U was overexpressed.
Ogata et al., "Interferon-inducible gene family 1-8U expression in colitis-associated colon cancer and severely inflamed mucosa in ulcerative colitis," Cancer Research, vol.