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5b, 5c, and 5f were also synthesized from disubstituted 1,4-naphthoquinones (4b, 4c, and 4f) an adaption of the procedure given for the monosubstituted 1,4- naphthoquinones .
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DNA damage and inhibition of akt pathway in MCF-7 cells and ehrlich tumor in mice treated with 1,4-naphthoquinones in combination with ascorbate," Oxidative Medicine and Cellular Longevity, vol.