After testosterone is converted to DHT, DHT is in turn normally metabolized into a relatively smaller quantity of 5 [alpha] -androstane-3 [alpha], 17 [beta] -diol (abbreviated as 3 [alpha] -Adiol), and a usually larger amount of 5 [alpha] -androstane-3 [beta], 17 [beta] -diol (abbreviated as 3 [beta] -Adiol).
Thanks to the work of Dawn Huo, PhD, at Meridian Valley Laboratory, you or your physician can request a blood test for testosterone, DHT, 3 [alpha] -Adiol, and 3 [beta] -Adiol (full name: 5 [alpha] -androstane-3 [beta], 17 [beta] -diol), check the relative proportions of each, and have a more clear idea about your cancer risk.
5a-Androstane-3 [beta], 17 [beta] -diol, an estrogenic metabolite of 5a-dihydrotestoserone, is a potent modulator of estrogen receptor [beta] (ER [beta]) in the ventral prostate of adult rats.
Estrogen receptor and the progression of prostate cancer: role of 5 [alpha] -androstane-3 [beta], 17 [beta] -diol. Endocr Re/at Cancer.
The root of Sesbania grandiflora provided a new natural compound: l,l'-binaphthalene-2,2'-diol (1) together with two known isoflavanoids (2-3).
Keywords: Sesbania grandiflora, l,l'-binaphthalene-2,2'-diol, biaryl natural product.
We report herein, the isolation and structural elucidation of a new natural compound: l,l'- binaphthalene-2,2'-diol (1) along with two known isoflavanoids (2-3) from the roots of S.
l, l'-binaphthalene-2,2'-diol (1) Colourless solid.
Based on the spectroscopy data which were observed including 1D and 2D NMR (see Table 1), the structure of compound 1 was established as l,l'- binaphthalene-2,2'-diol or 1,1'-bi-2-naphthol.