fruc·tose-bis·phos·phate al·dol·ase(fruk'tōs bis-fos'fāt al'dol-ās),
Fructose-1,6-bisphosphate triophosphate-lyase; an enzyme reversibly cleaving fructose 1,6-bisphosphate to dihydroxyacetone phosphate and glyceraldehyde 3-phosphate; also acts on certain ketose 1-phosphates; deficient in individuals with hereditary fructose intolerance (aldolase B isozyme); a deficiency of aldolase A leads to erythrocyte aldolase deficiency with nonspherocytic hemolytic anemia. Compare: hereditary fructose intolerance.
Synonym(s): 1, 6-diphosphofructose aldolase, 1-phosphofructaldolase, diphosphofructose aldolase, fructoaldolase, fructose 1, 6-bisphosphate triosephosphate-lyase, fructose 1, 6-diphosphate aldolase, fructose 1-monophosphate aldolase, fructose 1-phosphate aldolase, fructose-diphosphate aldolase, ketose-1-phosphate aldolase, phosphofructoaldolase, SMALDO, zymohexase
The enzyme involved in splitting fructose 1,6-diphosphate into dihydroxyacetone phosphate and phosphoglyceric aldehyde.