zoster immune globulin


Also found in: Dictionary, Thesaurus, Acronyms.
Related to zoster immune globulin: measles immune globulin

zos·ter im·mune glob·u·lin

a globulin fraction of pooled plasma from patients who have recovered from herpes zoster; used prophylactically for immunosuppressed children exposed to varicella and therapeutically to ameliorate varicella infection.

zoster immune globulin (ZIG)

Etymology: Gk, zoster + L, immunis, freedom, globulus, small sphere
a passive immunizing agent currently in limited experimental use for preventing or attenuating herpes zoster virus infection in immunosuppressed individuals who are at great risk of severe herpes zoster virus infection.

zos·ter im·mune glob·u·lin

(ZIG) (zos'tĕr i-myūn' glob'yū-lin)
Globulin fraction of pooled plasma from patients who have recovered from herpes zoster; used prophylactically for immunosuppressed children exposed to varicella and therapeutically to ameliorate varicella infection.
References in periodicals archive ?
These recommendations reflect the ACIP work group discussions and review of scientific evidence related to use of varicella zoster immune globulin conducted during the development of the ACIP statements on prevention of varicella as well as a review of published literature to include reports with immune globulins with high anti--varicella-zoster virus antibodies used outside the United States >4 days after exposure to varicella-zoster virus.
Because varicella zoster immune globulin might prolong the incubation period by [greater than or equal to]1 week, any patient who receives VariZIG should be observed closely for signs and symptoms of varicella for 28 days after exposure.
Limited data suggest that the incidence of varicella is comparable among persons who receive varicella zoster immune globulin within 4 days of exposure and those who receive it more than 4 days (up to 10 days) after exposure and attenuation of disease might be achieved with administration of varicella zoster immune globulin up to 10 days after exposure (2-5).
Varicella zoster immune globulin (VZIG) anticipated short supply and alternate product availability under an investigational new drug application expanded access protocol.
All seven women had household exposure to varicella, and varicella zoster immune globulin (VZIG) prophylaxis was indicated.