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zoledronate

   Also found in: Wikipedia 0.01 sec.
zoledronate
Zoledronic acid, Zometa® Osteoporosis A potent bisphosphonate used to ↓ fractures, ↓ bone pain Indications Postmenopausal osteoporosis, CA metastases to bone Adverse events Myalgia, pyrexia. Cf Biphosphonate, Osteoporosis.


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The scientists used the bisphosphonate drug zoledronate in combination with hormone therapy in a recent clinical trial, and found it to significantly reduce the recurrence of breast cancer in pre-menopausal women with oestrogen-receptor-positive breast cancer.
Recent studies have reported bisphosphonate use, specifically zoledronate and alendronate, as a risk factor for atrial fibrillation in women.
It has been seen primarily in patients with multiple myeloma or breast cancer who have received frequent doses of intravenous bisphosphonate medications such as zoledronate or pamidronate.
 
 
 
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