zileuton

zileuton /zi·leu·ton/ (zi-loo´ton) an inhibitor of leukotriene formation, used as an antiasthmatic.

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Zileuton (Zyflo)

A medication that interferes with the biosynthetic pathway that produces leukotrienes; used to help prevent asthma attacks.

Mentioned in: Leukotriene Inhibitors

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zileuton,

a bronchodilator and leukotriene pathway inhibitor.

indications This drug is used to treat allergic rhinitis and asthma.

contraindications Factors that prohibit the use of this drug are hepatic disease, liver function test results three times higher than upper limits, and known hypersensitivity to zileuton.

adverse effects Adverse effects of this drug include dizziness, insomnia, fatigue, paresthesias, headache, nausea, abdominal pain, dyspepsia, diarrhea, liver function test abnormalities, hives, myalgia, and asthenia.

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zileuton

Zyflo^® Clinical medicine An inhibitor of 5-lipoxygenase, an enzyme central to leukotriene synthesis, which mediates inflammatory responses Indications Asthma. See Asthma.