yohimbine


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yo·him·bine

(yō-him'bēn),
An alkaloid, the active principle of yohimbé, the bark of Corynanthe yohimbi (family Rubiaceae); it produces a competitive blockade, of limited duration, of adrenergic α-receptors; has also been used for its alleged aphrodisiac properties.

yohimbine

/yo·him·bine/ (yo-him´bēn) an alkaloid chemically similar to reserpine, from the bark of the yohimbe tree; it possesses alpha-adrenergic blocking properties and is used as the hydrochloride as a sympatholytic and mydriatic, and for the treatment of impotence.

yohimbine

(yō-hĭm′bēn′)
n.
An alkaloid, C21H26N2O3, that is derived from the bark of a tree, Pausinystalia johimbe, and is an alpha-blocker drug used in the form of its hydrochloride as a mydriatic, a treatment for erectile dysfunction, and formerly as an aphrodisiac.

yohimbine

Pharmacognosy
An indolamine alkaloid obtained from the bark of the West African yohimbe tree (Pausinystalia yohimbe) and others (e.g., Rauwolfia serpentina). Yohimbine is used for psychogenic and organic erectile dysfunction, increasing the inflow to and/or decreasing the outflow of blood from the penis by blocking the pre- and post-synaptic alpha-2 adrenoceptors. It has been studied for treating orthostatic hypotension and ischaemia due to autonomonic dysfunction in diabetes and narcotic overdose.

Toxicity
Tachcardia, hypertension, insomnia, nausea, palpitations, tremors, vomiting.

yohimbine

Pharmacognosy An alkaloid used to treat erectile dysfunction, which is chemically similar to reserpine; it may be of use for orthostatic hypotension and ischemic vascular disease caused by autonomonic dysfunction in DM, narcotic overdose, possibly acting to ↑ dopamine release, and for psychogenic and organic impotence, possibly ↑ inflow to and/or ↓ outflow of blood from the penis, with ↑ erection without ↑ sexual desire

yo·him·bine

(yō-him'bēn)
An alkaloid, the active principle of yohimbé, the bark of Corynanthe yohimbi; produces a competitive blockade, of limited duration, of adrenergic α-receptors; has also been used for its alleged aphrodisiac properties.

yo·him·bine

(yō-him'bēn)
An alkaloid, active principle of yohimbé, bark of Corynanthe yohimbi; it produces a competitive blockade, of limited duration, of adrenergic α-receptors; has also been used for its alleged aphrodisiac properties.

yohimbine (yōhim´bēn´),

n an alkaloid, the active principle comes from the bark of
Corynanthe johimbe. It produces a competitive blockage of limited duration of α-adrenergic receptors. It has also been used for its alleged aphrodisiac properties.

yohimbine

an α2 adrenoceptor antagonist used to reverse sedation produced by α2 adrenoceptor agonists such as xylazine.

yohimbine challenge test
used as a test for cataplexy in dogs; after administration, there is a marked reduction in the number and severity of clinical signs.
References in periodicals archive ?
Yohimbine for erectile dysfunction: a systematic review and meta-analysis of randomized clinical trials.
Consumption of Yohimbine may cause unwanted side effects, the health services said.
A 54-year-old man was admitted to the intensive care unit after ingesting multiple pills of Tylenol and Extenze, a product that contains yohimbine.
Yohimbine can bind to the same receptors, blocking the effects of adrenaline and allowing more insulin to be released.
Mifepristone in the central nucleus of the amygdala reduces yohimbine stress-induced reinstatement of ethanol-seeking.
The scent carries two chemicals - phenylethylamine (the "love drug") and yohimbine, an aphrodisiac, to give the maze an irresistible appeal.
Some chemicals, such as DMAA, PEA, or ephedrine, and extracts of plants such as kratom, yohimbine, or kava have been challenged by the FDA as being unsafe.
Several substances, such as ephedrine, synephrine and yohimbine, have been in the regulatory spotlight for years due to their connection to serious health issues such as kidney failure, seizures and heart problems.
In order to test the different stress hormones, the cognition psychologists used three substances - a placebo, the stress hormone hydrocortisone and yohimbine, which ensures that the stress hormone noradrenaline stays active longer.
Amitraz-induced glucose intolerance in rats: antagonism by yohimbine but not by prazosin.
2] antagonists such as yohimbine and atipamezole have been used in dogs (6).
The products were all found to contain yohimbine, an ingredient banned in the UAE by a ministerial resolution in 1988 because it causes cardiovascular side effects, heart failure and even death.