xeroderma /xe·ro·der·ma/ (zēr″o-der´mah) a mild form of ichthyosis, marked by a dry, rough, discolored state of the skin.xerodermat´ic
xeroderma
xeroderma [ze″ro-der´mah]
xeroderma,
xeroderma
xeroderma pigmento´sum a rare pigmentary and atrophic autosomal recessive disease in which extreme cutaneous sensitivity to ultraviolet light results from an enzyme deficiency in the repair of DNA damaged by ultraviolet light. It begins in childhood, with early development of excessive freckling, telangiectases, keratomas, papillomas, and malignancies in sun-exposed skin, severe opthalmologic abnormalities, and, in some cases, neurological disorders.
xe·ro·der·ma (zîr  -dûr m ) or xe·ro·der·mi·a (-m -)n. Excessive or abnormal dryness of the skin, as in ichthyosis. |
xeroderma
[zir′ədur′mə]
Etymology: Gk, xeros, dry, derma, skin
See icthyosis.
xeroderma [ze″ro-der´mah]
excessive dryness of the skin, a mild form of ichthyosis.
xeroderma pigmento´sum a rare and often fatal pigmentary and atrophic disease in which the skin and eyes are extremely sensitive to light. It begins in childhood and progresses to early development of excessive freckling, telangiectases, keratoses, papillomas, carcinoma, and melanoma. Ocular symptoms include photophobia, opacities, and tumors. It is inherited as an autosomal recessive trait involving a defect in the enzymes active in the repair of DNA damaged by ultraviolet irradiation. Subtypes of this disorder have been identified by the capacity for DNA repair. Total protection from sunlight prevents the development of lesions.
xeroderma,
n a chronic skin condition characterized by dryness and roughness.
xeroderma pigmentosum,
n an eruption of exposed skin occurring in childhood and characterized by numerous pigmental spots resembling freckles, larger atrophic lesions eventually resulting in glossy white thinning of the skin surrounded by telangiectases, and multiple solar keratoses that undergo malignant changes at an early age. This results from a single-gene autosomal recessive disorder.
xeroderma
a mild form of ichthyosis; excessive dryness of the skin.
xeroderma
Dry skin, see there
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