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xenobiotics

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xenobiotics,
n.pl potentially harm-ful, lipid-soluble chemicals that are foreign to the human body.

xenobiotics
foreign organic compounds not produced in metabolism.


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Both organic anions and xenobiotics in the blood use the same organic anion transporters (OATs) for entry into proximal tubule cells and they then exit these cells through ATP dependent ABCC2 (MRP2) and ABCC4 (MRP4), cassette transporters located at the luminal membrane of the cells (Sekine et al.
In brain tissue, GSTs function as scavengers that eliminate the formation of intracellular free radicals that are generated from the metabolism of drugs, toxins such as pesticides, or xenobiotics.
More xenobiotic compounds including the most recently "fancied" nanoparticles continue to find their way into the environmental milieu, increasing the accessibility of other xenobiotics into cells and their permeation through various blood organ barriers (BOB).
 
 
 
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