xanthine dehydrogenase

Also found in: Acronyms.

xan·thine de·hy·dro·gen·ase

an oxidoreductase oxidizing xanthine to urate with NAD+ as the oxidant. A lower rate of oxidation is observed in individuals with molybdenum cofactor deficiency.
References in periodicals archive ?
Mutational analysis of the xanthine dehydrogenase gene in a Turkish family with autosomal recessive classical xanthinuria.
Coding/regulatory region polymorphism discovery results for aldehyde oxidase, sulfate oxidase, and xanthine dehydrogenase.
When the enzyme is deficient, adenine is not salvaged to AMP, but instead is oxidized to 8-hydroxyadenine and 2,8-dihydroxyadenine by xanthine dehydrogenase (XDH).
Effect of cassia oils on serum and hepatic uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver.
Another important aspect of SH oxidation is conversion of xanthine dehydrogenase to xanthine oxidase.
In higher organisms, they fall into only two categories: xanthine dehydrogenases are involved in metabolic pathways; sulfite oxidases catalyse a small but important set of reactions involved in brain development.