wound hypoxia

wound hypoxia

stimulation of deep tissue healing by reduced tissue oxygenation; severe or prolonged wound hypoxia predisposes to anaerobic microorganism colonization
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Macrophages and wound hypoxia are the two predominant factors controlling the wound angiogenesis.
Hypoxaemia, anaemia and heart failure are systemic conditions that can cause wound hypoxia and may require medical intervention.
Increased oedema or decreased capillary density will cause wound hypoxia.
Wound hypoxia predisposes tissue to bacterial infection because the leukocyte's oxidative phosphorylation bactericidal activities are severely impeded without normal tissue oxygen levels.
Other studies have shown that tourniquet use increases postoperative wound hypoxia (Clark et al 2001) with possible consequent delayed healing and wound infection.