salmon

(redirected from whitefish)
Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

calcitonin (salmon)

APO-Calcitonin, Calcimar, Caltine, Fortical, Miacalcic (UK), Miacalcin, Miacalcin Nasal Spray, Sandoz Calcitonin

Pharmacologic class: Hormone (calcium-lowering)

Therapeutic class: Hypocalcemic

Pregnancy risk category C

Action

Directly affects bone, kidney, and GI tract. Decreases osteoclastic osteolysis in bone; also reduces mineral release and collagen breakdown in bone and promotes renal excretion of calcium. In pain relief, acts through prostaglandin inhibition, pain threshold modification, or beta-endorphin stimulation.

Availability

Injection: 0.5 mg/ml (human), 1 mg/ml (human), 200 international units/ml in 2-ml vials (salmon)

Nasal spray (salmon): 200 international units/actuation, metered nasal spray in 3.7 ml-bottle

Indications and dosages

Postmenopausal osteoporosis

Adults:Calcitonin (salmon)-100 international units/day I.M. or subcutaneously, or 200 international units/day intranasally with concurrent supplemental calcium and vitamin D

Paget's disease of bone (osteitis deformans)

Adults:Calcitonin (salmon)-Initially, 100 international units/day I.M. or subcutaneously; after titration, maintenance dosage is 50 to 100 international units daily or every other day (three times weekly). Calcitonin (human)-0.5 mg I.M. or subcutaneously daily, reduced to 0.25 mg daily.

Hypercalcemia

Adults:Calcitonin (salmon)-4 international units/kg I.M. or subcutaneously q 12 hours; after 1 or 2 days, may increase to 8 international units/kg q 12 hours; after 2 more days, may increase further, if needed, to 8 international units q 6 hours.

Contraindications

• Hypersensitivity to drug or salmon
• Pregnancy or breastfeeding

Precautions

Use cautiously in:
• renal insufficiency, pernicious anemia
• children.

Administration

Before salmon calcitonin therapy begins, perform skin test, if prescribed. Don't give drug if patient has positive reaction. Have epinephrine available.
• Bring nasal spray to room temperature before using.
• Give intranasal dose as one spray in one nostril daily; alternate nostrils every day.
• To minimize adverse effects, give at bedtime.
• Rotate injection sites to decrease inflammatory reactions.

Adverse reactions

CNS: headache, weakness, dizziness, paresthesia

CV: chest pain

EENT: epistaxis, nasal irritation, rhinitis

GI: nausea, vomiting, diarrhea, epigastric pain or discomfort

GU: urinary frequency

Musculoskeletal: arthralgia, back pain

Respiratory: dyspnea

Skin: rash

Other: altered taste, allergic reactions including facial flushing, swelling, and anaphylaxis

Interactions

Drug-drug.Previous use of bisphosphonates (alendronate, etidronate, pamidronate, risedronate): decreased response to calcitonin

Patient monitoring

• Monitor for adverse reactions during first few days of therapy.
• Assess alkaline phosphatase level and 24-hour urinary excretion of hydroxyproline.
• Check urine for casts.
• Monitor serum electrolyte and calcium levels.

Patient teaching

• Instruct patient to take drug before bedtime to lessen GI upset. Tell him to call prescriber if he can't maintain his usual diet because of GI upset.
• Inform patient using nasal spray that runny nose, sneezing, and nasal irritation may occur during first several days as he adjusts to spray.
• Instruct patient to bring nasal spray to room temperature before using.
• Advise patient to blow nose before using spray, to take intranasal dose as one spray in one nostril daily, and to alternate nostrils with each dose.
• Tell patient to discard unrefrigerated bottles of calcitonin (salmon) nasal spray after 30 days.
• Encourage patient to consume a diet rich in calcium and vitamin D.
• As appropriate, review all other significant adverse reactions and interactions, especially those related to the drugs mentioned above.

Relating to mucocutaneous lesions with a ‘salmon’ colour

salmon

farmed finfish; many species in the genera Salmo and Oncorhyncus.

salmon louse
Lepeophtherius salmonis.
salmon poisoning, salmon disease
a disease of dogs and other canids which eat salmon from streams in the Pacific Northwest of the USA, and caused by neorickettsia helminthoeca. The infection is transmitted by the fluke, Nanophyetus salmincola, parasitic in the salmon. The disease in dogs is characterized by fever, ocular discharge and edema of the eyelids, followed by vomiting, then diarrhea and later severe dysentery and death in untreated cases. See also elokomin fluke fever.
References in periodicals archive ?
Since that first encounter, Whitefish Marketing were selected to build the new BitSafe website, in keeping the much discussed need for a responsive design and simple user-experience functionality.
Ira Kirsche of Hungarian Kosher Foods said his market ordinarily would get 200 to 300 pounds of whitefish daily this time of year, but has had to settle for 10 to 20 pounds.
The relationship with Cambrian was a natural evolution," added Kris Laamanen, COO for both Helios Developments and Helios Whitefish River First Nation.
Legends members now receive $6 per pound for pin-boned lake whitefish fillets at the plant for product meeting Legends standards.
The Prime Minister's strategy unit last year called for additional cuts to the whitefish fleets, and for 30pc of the industry to voluntarily stop working for up to four years, warning that cod, haddock and plaice reserves had to be protected.
Meanwhile, perch fry are dying off because they cannot get enough to eat, and hungry whitefish are trying to consume the zebra mussels, which are tearing their insides apart.
To get to Whitefish from the East Coast means a series of smaller and smaller planes, until the last leg from Salt Lake City, when you are basically shoved into a lawn mower with wings.
And finally, Gary Ohs of Montana's Whitefish area (some 15 miles north of Kalispell) intended to deposit some $9,000 in cash at his bank on June 30.
A lack of working capital in the aquaculture industry is stifling the development of marine whitefish such as cod, halibut and haddock, said Alastair Barge, chairman of the British Marine Finfish Association.
Tyke division: A final--Fort William (7) vs Whitefish River (8).
The letter refers to the "assault of Ramsey Whitefish.
By day, hike miles of trails on Big Mountain, try fly-fishing, or arrange for horseback riding or a day of boating on Whitefish Lake with Montana Adventure Company (877/223-0745).