white sponge nevus

nevus /ne·vus/ (ne´vus) pl. ne´vi   [L.]

1. any congenital skin lesion; a birthmark.

2. a type of hamartoma representing a circumscribed stable malformation of the skin and occasionally of the oral mucosa, which is not due to external causes; the excess (or deficiency) of tissue may involve epidermal, connective tissue, adnexal, nervous, or vascular elements.

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balloon cell nevus  an intradermal nevus consisting of balloon cells with pale cytoplasm that contains large vacuoles formed of altered melanosomes.

blue nevus  a dark blue nodular lesion composed of closely grouped melanocytes and melanophages situated in the mid-dermis.

blue rubber bleb nevus  a hereditary condition marked by multiple bluish cutaneous hemangiomas with soft raised centers, frequently associated with hemangiomas of the gastrointestinal tract.

cellular blue nevus  a large blue to blue-black, multilobulated, well-circumscribed, nodular tumor composed of melanocytes and spindle cells, tending to occur on the buttocks and sacrococcygeal region and having a low incidence of transformation to melanoma.

compound nevus  a nevocytic nevus composed of fully formed nests of nevus cells in the epidermis and newly forming ones in the dermis.

connective tissue nevus  any of a group of hamartomas involving various components of the connective tissue, usually present at birth or soon after.

dysplastic nevus  an acquired atypical nevus with an irregular border, indistinct margin, and mixed coloration, characterized by intraepidermal melanocytic dysplasia and often a precursor of malignant melanoma.

nevus flam´meus  a common congenital vascular malformation involving mature capillaries, ranging from pink (salmon patch) to dark bluish red (port-wine stain) and usually occurring on the face and neck.

giant congenital pigmented nevus , giant hairy nevus, giant pigmented nevus any of a group of large, darkly pigmented, hairy nevi, present at birth; they are associated with other cutaneous and subcutaneous lesions, neurofibromatosis, and leptomeningeal melanocytosis and exhibit a predisposition to the development of malignant melanoma.

halo nevus  a pigmented nevus surrounded by a ring of depigmentation.

intradermal nevus  a nevocytic nevus, clinically indistinguishable from compound nevus, in which the nests of nevus cells lie exclusively within the dermis.

nevus of Ito  a mongolian spot–like lesion similar to nevus of Ota but localized to areas of distribution of the posterior supraclavicular and lateral cutaneous brachial nerves.

junction nevus  a nevocytic nevus in which the nests of nevus cells are confined to the dermoepidermal junction.

nevus lipomato´sus  nevolipoma.

nevocytic nevus , nevus cell nevus a tumor composed of nests of nevus cells, usually presenting as tan to brown small macules or papules with well-defined, rounded borders; they are subclassified as compound, intradermal, and junction.

nevus of Ota , Ota's nevus a mongolian spot–like lesion usually present at birth, involving the conjunctiva and lids, as well as adjacent facial skin, sclera, ocular muscles, periosteum, and buccal mucosa, usually unilaterally.

pigmented nevus  a nevus containing melanin, usually restricted to nevocytic nevi and moles.

sebaceous nevus , nevus sebaceus of Jadassohn a syndrome characterized by single or linear hamartomas of the scalp, face, or neck that may change through life; neurologic symptoms and ophthalmic abnormalities may be present. Over time, some lesions become nodular and tend to develop benign or malignant adnexal tumors or basal cell carcinoma.

nevus spi´lus  a smooth, tan to brown, macular nevus composed of melanocytes, and speckled with smaller, darker macules.

spindle and epithelioid cell nevus  a benign compound nevus, seen usually in children, composed of dermal spindle and epithelioid cells, resembling malignant melanoma histologically and appearing as a smoothish, raised, firm, pink to purplish nodule or papule.

nevus spongio´sus al´bus muco´sae  white sponge n.

nevus uni´us la´teris  a verrucous epidermal nevus occurring as a linear band, patch, or streak, usually along the margin between two neuromeres.

vascular nevus , nevus vascula´ris, nevus vasculo´sus a reddish swelling or patch on the skin due to hypertrophy of the skin capillaries.

white sponge nevus  a benign, congenital, inherited disorder characterized by extensive spongy whiteness and gray-white, soft, fissured lesions of the mucous membranes, especially of the oral mucosa.

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white sponge nevus

n.

A hereditary mucosal keratosis of the mouth characterized by a thickened white spongy fold of mucosa.

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nevus (nē´vus),

n a circumscribed new growth of congenital origin that may be vascular (resulting from hypertrophy of blood or lymph vessels) or nonvascular (with epidermal and connective tissue predominating).

nevus, blue,

n a benign neoplasm characterized by heavily pigmented spindle cells deep in the tissue; appears clinically as a dark mole.

Blue nevus.

nevus, cellular pigmented,

n a nevus composed of melanin-producing “nevus” cells.

nevus, compound,

n a nevus in which the melanin-producing nevus cells are found in the epidermis and dermis: the intradermal nevus plus the junctional nevus.

nevus, intradermal,

n a nevus in which the melanin-producing nevus cells are found only in the dermis.

nevus, junctional,

n a nevus in which the melanin-producing nevus cells are found within the epidermis at the junction with the dermis.

nevus, pigmented,

n a dark-colored, benign neoplasm characterized by nevus cells. Junctional, intradermal, and compound types are recognized. Melanomas (malignant neoplasms) may develop from junctional or compound nevi.

nevus, white sponge (Cannon's disease; white folded gingivostomatitis),

n an inherited disease of the oral mucosa characterized by generalized white mucosal surfaces with a spongelike appearance.

White sponge nevus.

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white sponge nevus

Dermatology An AD lesion characterized by variably-sized, painless, albescent plaques which, by LM, display a 'basket-weave' epithelium, hyperparakeratosis and acanthosis; WSNs occur on the mucosa of the nasopharynx, mouth, esophagus, larynx, vagina, and anus, WSNs may respond to penicillin