Such a therapy could benefit patients with the advanced wet AMD as well as those with other ocular indications with a scarring component such as proliferative vitreoretinopathy
(PVR) and proliferative diabetic retinopathy (PDR).
The first approval is a surgical microscope from Carl Zeiss Meditec AG, which can be used for a number of surgical pro cedures concerning the eye, including complex detachments necessitated by proliferative diabetic retinopathy and proliferative vitreoretinopathy
Two-year-old Joe has a very rare condition called Familial Exudative Vitreoretinopathy
, a genetic eye disorder which affects the growth and development of blood vessels in the retina of the eye.
The 19-year-old was born with Familial Exudative Vitreoretinopathy
- a rare, progressive eye disorder - so his parents were warned very early on that he would one day lose his sight.
At WRAMC, common causes of BCVA worse than 20/200 were traumatic optic neuropathy, corneal scarring/decompensation, proliferative vitreoretinopathy
, and primary enucleation/evisceration.
Patients: Patients included in this study were those clinically diagnosed as Eales' disease by the criteria described by Das et al (1) and non-Eales' patients with non-infective diseases such as proliferative diabetic retinopathy, retinal detachment and proliferative vitreoretinopathy
Immusol's lead drug candidate is in Phase II clinical testing for Proliferative Vitreoretinopathy
(PVR), a proliferative disease of the eye.
S] I have two children that were diagnosed with Familial Exudative Vitreoretinopathy
(FEVR) and are now both legally blind.
Additionally, Promedior plans to accelerate the development of its drug candidate for ophthalmic indications, PRM-167 (rhPTX-2 variant for intravitreal injection), which is designed to be optimized for fibrovascular retinal diseases such as age-related macular degeneration (AMD), diabetic retinopathy and proliferative vitreoretinopathy
It may be stiffer and less mobile in longstanding or recurrent detachments when some proliferative vitreoretinopathy
Although previous studies (16) have reported a possible role for the retinal pigment epithelium in the pathogenesis of VPTR similar to that in proliferative vitreoretinopathy
, we did not see evidence to support this in the present case.
Promedior is developing PRM-167 (rPTX-2 variant for intravitreal injection) for the treatment of fibroproliferative retinal diseases like AMD, diabetic retinopathy and proliferative vitreoretinopathy
(PVR, retinal detachment).