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menadione
(redirected from vitamin K3)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
menadione /men·a·di·one/ (men″ah-di´ōn) vitamin K3.
1. a synthetic fat-soluble vitamin that can be converted in the body to active vitamin K.
2. the basic double ring quinone structure that is the parent structure of the related compounds with vitamin K activity, which can be formed by addition of long side chain substituents.

men·a·di·one (mn-dn)
n.
A synthetic vitamin K derivative occurring as a yellow crystalline powder and used as a vitamin K supplement.

Menadione
A synthetic form of vitamin K. It is sometimes called vitamin K3.
Mentioned in: Vitamin Toxicity

menadione
[men′ədi·ōn]
a synthetic fat-soluble provitamin that can be chemically converted in the body to active vitamin K. It is used as a source of vitamin K in the treatment of hypoprothrombinemia associated with vitamin K deficiency, as occurs in hepatic or biliary disease or malabsorption syndromes, or after administration of salicylates, anticoagulants, or certain antibiotics. It is administered orally or intramuscularly. See also vitamin K. Also called vitamin K3.

menadione [men″ah-di´ōn] vitamin K3.
1. a synthetic fat-soluble vitamin that can be converted in the body to active vitamin K; administered orally or intramuscularly. See vitamin.
2. the basic double ring quinone structure that is the parent structure of the related compounds with vitamin K activity, which can be formed by addition of long side chain substituents.

menadione
a fat-soluble synthetic derivative of vitamin K used in the treatment and prevention of deficiency. Called also vitamin K3.

menadione sodium bisulfite
is soluble in water and can be given by injection for a rapid effect.


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44) While vitamins K1 and K2 are safe and effective, vitamin K3 is potentially toxic and its use has been limited to treating aggressive cancers.
Vitamin K comprises three main forms: vitamin K1 or phylloquinone which is found in green plants; vitamin K2 or the menaquinone family which is synthesised by bacteria in the large intes tine; and vitamin K3 or menadione which is a synthetic, water-soluble form that has been utilised in animal feeds.
BACKGROUND: To evaluate the efficacy of vitamin K3 (VK3) against pancreatic cancer, the molecular mechanism of VK3 or gemcitabine (GEM)-induced inhibition of proliferation was characterized.
 
 
 
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