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vitamin B6 -dependency syndromes |
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vitamin B6 -dependency syndromes A group of functional or structural enzyme defects that respond to a megadoses–50-100-fold > minimum daily requirements of pyridoxine Examples Vitamin B6-dependent convulsions,
vitamin B6-responsive anemia, xanthurenic aciduria, cystathioninuria, homocystinuria, possibly due to a defective structure of the apoenzyme, its coenzyme binding site or coenzyme synthesis Clinical Predominantly neurologic–eg,
mental retardation, psychiatric Sx, seizures, convulsions, ataxia, spasticity, peripheral neuropathy How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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