vitamin B6


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vi·ta·min B6

pyridoxine and related compounds (pyridoxal; pyridoxamine).

vitamin B6

vitamin B6

A widely used generic term for the water-soluble derivatives of 2-methyl pyridine, including pyridoxine, pyridoxal and pyridoxamine, which are critical to immune function, neural transmission, metabolism and red cell synthesis. Vitamin B6 is obtained in the diet in avocados, bananas, brown rice, corn, fish, meat, nuts, poultry and whole grains; pharmacologic doses may be effective for carpal tunnel syndrome, seizures in infants and in premenstrual syndrome.
 
Toxicity
Severe nerve damage, which requires months for recuperation.

megavitamin therapy

The administration of excess or 'hyper-doses' of water-soluble vitamins, either physician-guided–eg, to treat neuropathies, or self-prescribed by health-food advocates. See Decavitamin, Orthomolecular medicine, Vitamin.
Megavitamins, adverse effects  
Thiamin CNS hyperresponsiveness–convulsions, Parkinson's disease–thiamin antagonizes l-dopa, sensory neuropathy–destruction of dorsal axon roots
Niacin/nicotinic acid & niacinamide/nicotinamide Exacerbation of asthma–histamine release, cardiac disease–arrhythmias, GI symptoms, eg nausea, vomiting, diarrhea, anorexia, DM–hyperglycemia, gout–↑ uric acid, liver disease–enzyme leakage, hepatocellular injury, portal fibrosis or massive necrosis, cholestatic jaundice, peptic ulcer disease–histamine release, ↑ acidity, skin disease
Vitamin B6 Paresthesia, headaches, asthenia, irritability
Vitamin C ↑ Iron absorption, possibly iron overload, evoking diarrhea, renal calculus formation and possibly inhibiting the bacteriolytic activity of neutrophils, G6PD deficiency–↑ red cell lysis, megaloblastic anemia–↓ vitamin B12 absorption, nephrolithiasis–oxaluria Diagn Clin Testing 1990; 28:27  

vi·ta·min B6

(vīt'ă-min)
Pyridoxine and related compounds (pyridoxal; pyridoxamine).

vitamin B,

n a water-soluble vitamin found in nutritional and brewer's yeasts, beans, seeds, wheat germ, nuts, bananas, and avocados. Has been used to maintain cardiovascular health, to remedy deficiencies—including lower levels from taking hydralazine, isoniazid, MAOIs, penicillamine, and theophylline—and to treat morning sickness, asthma, carpal tunnel syndrome, depression, seborrheic dermatitis. Is also used to prevent kidney stones and the side effects from theophylline and photosensitivity. Megadoses may cause sensory neuropathy. Supplementation is contraindicated for those taking levodopa. Caution is advised for children and pregnant or lactating women, for whom the maximum daily dose is 100 mg. May cause neuropathy at large doses. Also called
pyridoxine hydrochloride or
pyridoxal-5-phosphate.

vi·ta·min B6

(vītă-min)
Pyridoxine and related compounds (e.g., pyridoxal; pyridoxamine).
References in periodicals archive ?
All the women took vitamin B6 (as pyridoxine) 100 milligrams daily for two weeks, after which repeat testing found that twelve of the fourteen (86%) no longer had the problem
In line with a case reported from Tunisia in 2012,4 we report a case of a middle aged female who developed severe axonal sensory and motor neuropathy leading to quadriparesis three months after she was started on anti- TB treatment (ATT) without vitamin B6 prophylaxis.
Of all the patients, 9 patients had homocysteine level above the 15mol/L, 26 had folic acid level below 3 ng/ml, one had vitamin B12 level below 150 pmol/L, and two had vitamin B6 level below 30 nmol/L.
Relatively little has been published concerning the effects of exercise on vitamin B6 metabolism and maltodextrin supplementation.
Dr Ivo Tews, Lecturer in Structural Biology at the University of Southampton, says: "The structural studies explain how these vital enzymes are activated and show the substrate of vitamin B6 biosynthesis bound to give insights into the chemistry of PLP biosynthesis.
MEETING YOUR VITAMIN B6 AND B12 NEEDS THROUGH DIET The Recommended Dietary Allowance (RDA) for vitamin B6 for men age 50 and older is 1.
Using this method they identified PdxA and PdxJ, enzymes involved in vitamin B6 biosythesis, as being important factors for the chronic colonization of mice by H.
It might be too soon to start popping supplements, but high levels of vitamin B6 may reduce lung cancer risk, scientists report June 16 in the Journal of the American Medical Association.
to produce vitamin B6, announced Guangji Pharma today.
POTASSIUM, calcium, vitamin A, vitamin B6, zinc, pantothenic acid, biotin, selenium, iodine, magnesium, vitamin B12, niacin, riboflavin, thiamine, chlorine, sodium, iron, folic acid, vitamin C, phosphorus: these are the vital vitamins and minerals I take every day.
23 issue of Archives of Internal Medicine suggests that taking folic acid and vitamin B6 and B12 may help women preserve their eyesight as they age.