vitamin A poisoning

(redirected from vitamin A intoxication)

vitamin A poisoning

A potentially fatal condition evoked by an acute or chronic excess of vitamin A (> 20,000 IU) for more than two weeks.

Clinical findings
Bone pain, dry skin, gastrointestinal complaints (nausea, vomiting, constipation, diarrhoea), increased intracranial pressure, poor growth in children; affected infants may develop bulging fontanelles, craniotabes (softening of skull bones), pseudotumour cerebri, papilledema, drowsiness, severe headaches, insomnia, jaundice, menstrual disorders, stress, weight loss, irritability, decreased appetite, pruritis, hair loss, seborrhoea, and cracking at corners of mouth.
References in periodicals archive ?
In young children, administration of low doses, of 20,000 to 60,000 units per day for a period of one to three months has resulted in vitamin A intoxication.