28) Basing their work on evidence that pyridoxamine could prevent development of kidney damage in experimental models of diabetes, scientists at the University of South Carolina hypothesized in 2003 that this B6 vitamer
would provide similar benefits in experimental subjects that, while not diabetic, were obese.
patent in July of 2002, describing compositions comprised of individual vitamers
of non-alpha tocopherols, e.
Chromatograms of a plasma and a whole-blood sample before and after addition of the riboflavin vitamers
are shown in Fig.
concentrations (nmol/L), as determined by this assay, were <4 for PMP, 87 for PLP, <0.
concentrations (medians and interquartile ranges) for the whole study group before intervention are listed in Table 1.
Additionally, different types of anticoagulants have been used for the preparation of plasma, and this may influence sample stability and relative vitamer
Vitamin B-complex refers to a group of water-soluble vitamers
that although co-exist together are distinct in chemical structure and functions.
The formulation supplies only the best-utilized B vitamin forms, or vitamers
, substituting naturally fully active folate (as Quatrefolic[R] methyl-tetra-hydro-folate, or MTHF) for synthetic folic acid, and a generous amount of fully active B12 (as methylcobalamin).
Examples of such tests include thyroid-stimulating hormone, human chorionic gonadotropin (HCG), prostate-specific antigen, troponin I, natriuretic peptides, carcinoembryonic antigen, luteinizing hormone, hydroxylated vitamin D vitamers
, Epstein-Barr virus, and BK virus, all of which have complex molecular forms and closely related molecules that in many cases vary under different pathophysiologic conditions.
, aminotransferases in various tissues and organs are often used as the basis for evaluating vitamin B6 status in animals, because these enzymes require PLP as a coenzyme.
are absorbed with different efficiencies
6] (pyridoxal phosphate) by HPLC and fluorescence detection involving precolumn derivatization of plasma vitamers
with sodium bisulfite (19).