virologic failure


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virologic failure

Antiretroviral therapy failure, see there.
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References in periodicals archive ?
Comparison of Three Different FDA-Approved Plasma HIV-1 RNA Assay Platforms Confirms the Virologic Failure Endpoint of 200 Copies per Milliliter Despite Improved Assay Sensitivity.
The researchers counted how many people had a virologic failure in 1997-1998, 1999-2000, 2001-2002, 20032004, 2005-2006, 2007-2008, and 2009-2011.
Immunologic and virologic failure alter first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children.
Knobel H, Guelar A, Carmona A, et al, Virologic outcome and predictors of virologic failure of highly active antiretroviral therapy containing protease inhibitors.
Although there may be some overlap between the definitions of blips and persistent low-level viremia, the clinical significance of these events is quite different, as patients with low-level viremia experience higher rates of virologic failure and immune activation whereas those with blips do not.
The higher discontinuation rate in women, which was driven by reasons other than virologic failure, highlights the need for additional efforts to retain diverse populations in studies," the researchers concluded.
After week eight, the GS 9137 20 mg arm was closed due to a high rate of virologic failure.
Despite this progress, there are still those who experience virologic failure and others who have been on treatment for many years with the emergence of highly drug-resistant HIV that limits their ability to achieve viral suppression.
Thus, the selection of 2 mutations, each of which may preexist as minority species, leads to virologic failure with this regimen.
The panel has recommended resistance testing to aid in choosing a regimen for individuals with virologic failure on an initial regimen or to help guide management after numerous regimens have failed.
The association between primary antiretroviral resistance and HAART virologic failure in a developing set.
One patient in the eight week dosing group and one patient in the oral regimen group met protocol defined virologic failure criteria; neither patient had evidence of resistance at failure.