virilization


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masculinization

 [mas″ku-lin-ĭ-za´shun]
1. the normal induction or development of male secondary sex characters in the male.
2. the induction or development of male secondary sex characters in the female or prepubertal male.
3. the condition of having such sex characters. Called also virilization.

vir·i·li·za·tion

(vir'i-li-zā'shŭn),
Production or acquisition of virilism.

virilization

/vir·il·iza·tion/ (vir″ĭ-lĭ-za´shun) masculinization; usually used for that occurring in a female or prepubertal male.

virilization

(vîr′ə-lĭ-zā′shən)
n.
Development of male secondary sexual characteristics.

vir′il·ize′ (-ə-līz′) v.

virilization

[vir′əlīzā′shən]
Etymology: L, virilis + atus, process
a process in which secondary male sexual characteristics are acquired by a female, usually as the result of adrenal dysfunction or hormonal medication. Also called masculinization, virilism. See also adrenal virilism.

virilization

Physical changes in a ♀ 2º to androgen excess Clinical Hirsutism, temporal balding, deepened voice, acne, enlarged clitoris and clitoral index–ratio between the sagittal and transverse diameters of the clitoris; the androgen excess may be
1. Adrenal, due to Cushing's syndrome, congenital enzyme deficiency–eg, 11– or 21–hydroxylase deficiency or neoplasia, either benign or malignant or.
2. Ovarian, due to hyperplasia–eg, polycystic ovaries or tumors–eg, arrhenoblastoma, steroid cell tumors or gynandroblastoma. Cf Hermaphroditism, Intersex, Precocious puberty, Virilism.

vir·i·li·za·tion

(vir'i-lī-zā'shŭn)
Production or acquisition of virilism.

virilization

induction or development of male secondary sex characters, especially the appearance of such changes in the female. Called also masculinization.
References in periodicals archive ?
The first step to a full diagnosis is checking for hirsutism, virilization, and acanthosis nigricans (which is associated with insulin resistance).
3 nmol/L) 2 SV Adult body odor and increased growth velocity at 5 years; basal 17OHP, 16 946 ng/dL (509 nmol/L) 6 SV Diagnosed at 10 years with significant virilization including clitoromegaly, hirsutism, muscular habitus, and low voice; bone age, 15 years at chronologic age of 10 years; elevated urinary 17-ketosteroids 7 NC Diagnosed at 28 years with hirsutism, male pattern baldness; basal 17OHP, 740 ng/dL (22 nmol/L); cosyntropin/stimulated 17OHP, 3460 ng/ dL (104 nmol/L); precocious puberty with menarche at age 8 years 7S (c) NC Diagnosed at 62 years secondary to family genetic studies; basal 17OHP, 813 ng/dL (24 nmol/L); cosyntropin/stimulated 17OHP, 7190 ng/ dL (216 nmol/L); menarche at age 9 years (a) 17OHP, 17-hydroxyprogesterone.
These tumors may be hormonally active and hypertension, diarrhea, flushing and virilization may occur as a result the secretion of catecholamine, vasoactive intestinal polypeptide, or androgenic hormone.
Androgen excess causes virilization of females, resulting in increased hirsutism, acne, menstrual abnormalities, clitoromegaly, and in its most severe form masculinization of the external genitalia.
Since the degree of Leydig cell damage in XXY is variable, serum testosterone and virilization in some individuals may be normal.
TABLE 1: PRESENTING SYMPTOMS OF PATIENTS Symptoms number of cases mass abdomen 9 pain abdomen 5 Cushing syndrome 2 giddiness, sweating 2 virilization 1 Table 2: Identified Cases Of Neuroblastomas In The Study Nb undifferentiated 03 Poorly differentiated 01 Differentiated 02 Ganglioneuroblastoma 01 TABLE 3: Comparison of a similar study conducted by Stewart et al and our study.
In women, it is measured in the investigation of hyperandrogenism, hirsutism, virilization, oligo/amenorrhea, acne, and infertility.
Our findings are also in line with other recent human data showing incomplete virilization in infant boys exposed to phthalates prenatally.
Goldman JM, Kapadia LJ, Virilization in a postmenopausal woman due to ovarian stromal hyperthecosis.
CAH may present with variety of clinical findings, such as virilization of the affected infants, signs of androgen excess, salt-wasting crisis secondary to aldosterone deficiency, or hormonal hypertension attributable to increased mineralocorticoids.
60% of the tumours are functional with adults presenting with cushing's syndrome, combined with virilization or virilization alone.
The associations between male genital development and phthalate exposure seen here are consistent with the phthalate-related syndrome of incomplete virilization that has been reported in prenatally exposed rodents.