virilization

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Related to virilisation: virilism

masculinization

 [mas″ku-lin-ĭ-za´shun]
1. the normal induction or development of male secondary sex characters in the male.
2. the induction or development of male secondary sex characters in the female or prepubertal male.
3. the condition of having such sex characters. Called also virilization.

vir·i·li·za·tion

(vir'i-li-zā'shŭn),
Production or acquisition of virilism.

virilization

/vir·il·iza·tion/ (vir″ĭ-lĭ-za´shun) masculinization; usually used for that occurring in a female or prepubertal male.

virilization

(vîr′ə-lĭ-zā′shən)
n.
Development of male secondary sexual characteristics.

vir′il·ize′ (-ə-līz′) v.

virilization

[vir′əlīzā′shən]
Etymology: L, virilis + atus, process
a process in which secondary male sexual characteristics are acquired by a female, usually as the result of adrenal dysfunction or hormonal medication. Also called masculinization, virilism. See also adrenal virilism.

virilization

Physical changes in a ♀ 2º to androgen excess Clinical Hirsutism, temporal balding, deepened voice, acne, enlarged clitoris and clitoral index–ratio between the sagittal and transverse diameters of the clitoris; the androgen excess may be
1. Adrenal, due to Cushing's syndrome, congenital enzyme deficiency–eg, 11– or 21–hydroxylase deficiency or neoplasia, either benign or malignant or.
2. Ovarian, due to hyperplasia–eg, polycystic ovaries or tumors–eg, arrhenoblastoma, steroid cell tumors or gynandroblastoma. Cf Hermaphroditism, Intersex, Precocious puberty, Virilism.

vir·i·li·za·tion

(vir'i-lī-zā'shŭn)
Production or acquisition of virilism.

virilization

induction or development of male secondary sex characters, especially the appearance of such changes in the female. Called also masculinization.
References in periodicals archive ?
Virilisation of the external genitalia without palpable gonads should arouse the suspicion of CAH and is an indication for prompt and emergency referral to an endocrine specialist.
However, females have virilisation of the external genitalia and should be recognised at birth.
Most of the clinicians think that the disease is incurable, but testosterone therapy has shown to induce virilisation in this and several other case reports in almost all cases with a variable effect on future fertility.
12) These mutations may result in different levels of sensitivity to androgens, leading to virilisation at puberty, despite childhood development as female with respect to the genitalia.
Here, we present a case of a 51year old lady who presented with hirsutism, virilisation of 14 year duration and was found to have steroid cell tumour of the left ovary measuring 12x12x9 cm.
The noticeable presentation of a patient with a Virilizing ovarian tumour is hirsutism and virilisation because of hyperandrogenism, as seen in this case.
Virilisation is a two phased process: first, there is defeminization like development of oligomenorrhea or amenorrhea, regression of the breasts and external genitalia, atrophy of the uterus and adnexa, and loss of the female body contour; second, there is masculinization which includes hirsutism, acne, clitoral enlargement, increased libido, sterility, enlargement of the larynx, deepening of the voice, increased muscle mass and temporal alopecia.
Here we present the case of a rare ovarian steroid cell tumor in a 32 yrs old woman who presented with virilisation.
9 patients presented with mass abdomen in which 5 of them had associated pain, 2 complained of giddiness and sweating, one had virilisation symptoms, 2 had shown criteria indicating Cushing's syndrome (fig 1).
Cushing syndrome is associated with adrenocortical adenoma (fig 1a) and virilisation is associated with adrenocortical carcinoma.
Virilisation was seen in adrenocortical carcinoma and Cushing syndrome seen in cases of adrenal adenoma (table 3).