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viral tropism

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viral tropism
n.
The specificity of a virus for a particular host tissue, determined in part by the interaction of viral surface structures with receptors present on the surface of the host cell.


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Pre-screening patients for viral tropism is therefore a necessary but cumbersome step in initiating this drug.
In addition, the introduction of either an R5 or an X4 antagonist might require the addition of an expensive new diagnostic test--the viral tropism assay that currently costs over $1,000--to the standard of care.
Other studies have used SARS-CoV S pseudotyped viruses for identifying receptors (24), examining viral tropism (25-27), and measuring neutralizing antibody responses (18,28-30).
 
 
 
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