Adjuvant docetaxel or vinorelbine
with or without trastuzumab for breast cancer.
Patients treated with LYNPARZA showed a statistically-significant and clinically-meaningful improvement in progression-free survival (PFS) compared with those who received chemotherapy (capecitabine, vinorelbine
After treated with vinorelbine
and/or gemcitabine as second- or third-line therapy, 46% of patients had stable disease.
Finalizado esse ciclo, iniciou-se o protocolo Gencitabina + Vinorelbine
, ambos administrados por via endovenosa.
tartrate injection was intravenously infused on the 1st and 8th days at the dose of 20-25 mg/m2, and cisplatin was intravenously infused on the 1st to 3rd days at the dose of 20-30 mg/m2.
It can also be treated with platinum-based drugs, and drugs such as capecitabine, eribulin, gemcitabine, ixabepilone, and vinorelbine
The alternatives assessed here were (L+C) compared to trastuzumab + capecitabine (T+C), trastuzumab + paclitaxel (T+P), trastuzumab + docetaxel (T+D), and trastuzumab + vinorelbine
The effect of oral vinorelbine
as maintenance therapy was investigated in a phase II multicenter clinical trial.
Platinum-based chemotherapy is used for some cases, as well as vinorelbine
, paclitaxel, gemcitabine and etoposid, which are rarely used in combination.
Phase II randomized trial comparing vinorelbine
plus cisplatin in patients with recurrent salivary gland malignancies.
Cisplatin and Vinorelbine
adjuvant chemotherapy was administered with no overt complications; however recurrence of the disease was discovered radiologically one year post-operatively in the form of a left hilar soft tissue mass with bony metastases.
The other example of CMA could be found in the study by the Southwest Oncology Group in which they compared the use of vinorelbine
plus cisplatin versus paclitaxel plus carboplatin in the treatment of advanced NSCLC found no statistically significant difference in survival rate or quality of life between the treatment arms.