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a vinca alkaloid used as an antineoplastic agent, primarily as a component of combination chemotherapy regimens for Hodgkin's disease, acute lymphoblastic leukemia, and non-Hodgkin's lymphomas, as well as in the treatment of other neoplastic disorders including Wilms' tumor, neuroblastoma, AIDS-associated Kaposi sarcoma, and rhabdomyosarcoma. Administered intravenously as the sulfate salt.
vincristine/vin·cris·tine/ (vin-kris´tēn) an antineoplastic vinca alkaloid; used as the sulfate salt in the treatment of various neoplasms, including Hodgkin's disease, acute lymphocytic leukemia, non-Hodgkin's lymphoma, Kaposi's sarcoma associated with AIDS, and neuroblastoma.
An alkaloid, C46H56N4O10, originally obtained from the Madagascar periwinkle and used in its sulfate form to treat acute leukemia and a variety of other neoplasms.
MOPPA 4-drug chemotherapy regimen for stage-III Hodgkin lymphoma.
Sterility, nausea, vomiting, immunosuppression, increased infections, myelosuppression, myelodysplasia, ANLL.
vincristineOncovin® AIDS A dimeric vinca alkaloid used to treat KS, thrombocytopenia, leukemias, lymphomas, solid tumors and other CAs which, like vinblastine, interrupts the mitotic spindle, causing lysis of proliferating cells Adverse effects Reversible peripheral neuropathy, constipation. Cf Vinblastine.
vincristineA vinca alkaloid anticancer drug used to treat LEUKAEMIA. The drug is on the WHO official list. A brand name is Oncovin.
a vinca alkaloid; the sulfate is used as an antineoplastic usually in combination with other antineoplastic agents.