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vincristine

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.02 sec.
vincristine /vin·cris·tine/ (vin-kris´tēn) an antineoplastic vinca alkaloid; used as the sulfate salt in the treatment of various neoplasms, including Hodgkin's disease, acute lymphocytic leukemia, non-Hodgkin's lymphoma, Kaposi's sarcoma associated with AIDS, and neuroblastoma.
vincristine [vin-kris´tēn]
a vinca alkaloid used as an antineoplastic agent, primarily as a component of combination chemotherapy regimens for Hodgkin's disease, acute lymphoblastic leukemia, and non-Hodgkin's lymphomas, as well as in the treatment of other neoplastic disorders including Wilms' tumor, neuroblastoma, AIDS-associated Kaposi sarcoma, and rhabdomyosarcoma. Administered intravenously as the sulfate salt.

vincristine
a vinca alkaloid; the sulfate is used as an antineoplastic usually in combination with other antineoplastic agents.

vincristine
Oncovin® AIDS A dimeric vinca alkaloid used to treat KS, thrombocytopenia, leukemias, lymphomas, solid tumors and other CAs which, like vinblastine, interrupts the mitotic spindle, causing lysis of proliferating cells Adverse effects Reversible peripheral neuropathy, constipation. Cf Vinblastine.


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In follow-up tests, the researchers took nerve cells in culture and treated their axons with the chemotherapy drug vincristine.
Patients received two cycles of ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine), MOPP/ABV (mechlorethamine, vincristine, procarbazine, and prednisone), or other ABVD-like chemotherapy.
Therefore, AHCC is safe and unlikely to result in increased toxicity when used in combination with commonly used chemotherapeutic agents such as Cyclophosphamide, Ifosfamide, Paclitaxel, Docetaxel, Irinotecan, Vincristine, interferon and Imatinib.
 
 
 
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