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vicious viscous hypothesis

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vicious viscous hypothesis
Kinetic hypothesis Hematology A hypothesis that attempts to explain the pathogenesis of the microvascular occlusions typical of sickle cell anemia; according to VVH, the ↑ in blood viscosity caused by the relatively inelastic sickled RBCs, slows blood flow in
the microcirculation; this slowing results in relative hypoxia, which favors further sickling of upstream RBCs, resulting in vascular occlusion and infarction


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