verapamil /ve·rap·a·mil/ (vĕ-rap´ah-mil) a calcium channel blocker that dilates coronary arteries and decreases myocardial oxygen demand, used as the hydrochloride salt in the treatment of angina pectoris and of hypertension and the treatment and prophylaxis of supraventricular tachyarrhythmias.
verapamil
verapamil
ve·rap·a·mil (v -r p -m l )n. A vasodilator that inhibits calcium activity, used to treat hypertension, angina pectoris, and certain cardiac arrhythmias. |
verapamil
[verap′əmil]
a calcium channel blocker.
indications It is prescribed for the treatment of vasospastic and exertional angina, supraventricular tachycardia, atrial fibrillation, and atrial flutter.
contraindications Severe left ventricular dysfunction, hypotension, cardiogenic shock, sick sinus syndrome, or second- or third-degree atrioventricular (AV) block prohibits its use.
adverse effects Among the more serious adverse effects are hypotension, peripheral edema, AV block, bradycardia, congestive heart failure, pulmonary edema, constipation, and dizziness.
verapamil
a calcium channel blocking agent used as a vasodilator and in the treatment of cardiac arrhythmias.
verapamil
Cardiology A CCB antiarrhythmic that slows transmission of impulses across the AV node and supresses the sinus node's intrinsic rhythm Indications Tachycardial supraventricular arrhythmias–eg, paroxysmal supraventricular
tachycardia, A Fib with tachyarrhythmias, atrial flutter with rapid conduction, and is the parenteral emergency drug of choice Adverse effects Constipation, slowed AV conduction and sinus node automaticity, peripheral edema; it is a standard agent
for managing HTN, especially in Pts with angina; it improves pain linked to obstructive cardiomyopathy, and prevents migraines Contraindications Severe left ventricular dysfunction, hypotension, sick sinus syndrome, 2º or 3º AV block, WPW,
heart failure, or in Pts with accessory bypass tracts, WPW syndrome, peripheral edema; caution in renal failure. See Calcium channel blocker, Therapeutic drug monitoring. Cf Beta blocker.
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