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venules

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venules (vēnˑ·yōōlz),
n.pl small blood vessels that merge with the veins and return blood from other tissues to the heart.


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The "Indications and Usage" section of the FDA-approved labeling (PI) states "RECOTHROM is indicated as an aid to hemostasis whenever oozing blood and minor bleeding from capillaries and small venules is accessible and control of bleeding by standard surgical techniques is ineffective or impractical.
Although the pathogenesis of hepatic SOS is not understood, it is thought to begin with injury to the hepatic venules.
Their characteristic histologic features include preserved nodal architecture, florid follicular hyperplasia with reactive germinal centers, protein and IgE deposits in germinal centers, germinal center necrosis, eosinophilic infiltrates, proliferation of post-capillary venules, sclerosis, polykaryocytes, eosinophilic folliculolysis, and prominent eosinophilic microabscesses (figure).
 
 
 
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