kinin

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kinin

 [ki´nin]
the generic term for any of the polypeptides related in amino acid sequence and physiological activity to bradykinin and kallidin, formed by kallikrein-mediated cleavage of kininogens. Kinins are plasma proteins that increase vascular permeability, interact with prostaglandins to cause pain and smooth muscle contraction and to increase the migration of white blood cells during the inflammatory process, and act as potent renal vasodilators to increase the renal excretion of sodium.

ki·nin

(kī'nin),
Polypeptide hormones that are released from diffuse stores and not from specialized tissue. they are rapidly inactivated at the site of release.
[G. kineō, to move, + -in]

kinin

/ki·nin/ (ki´nin) any of a group of vasoactive straight-chain polypeptides formed by kallikrein-catalyzed cleavage of kininogens; causing vasodilation and also altering vascular permeability.

kinin

(kī′nĭn)
n.
Any of various structurally related polypeptides, such as bradykinin, that act locally to induce vasodilation and contraction of smooth muscle.

kinin

[kī′nin]
any of a group of polypeptides with varying physiological activity, such as contraction of visceral smooth muscle, vascular permeability, and vasodilation. Two principal kinins, bradykinin and lysylbradykinin, are formed in the blood from precursor kininogens by the action of kallikrein and kinases.

ki·nin

(kī'nin)
One of a number of substances having pronounced physiologic effects. Some are polypeptides, formed in blood in various pathologic processes, which stimulate visceral smooth muscle but relax vascular smooth muscle, thus producing vasodilation.
[G. kineō, to move, + -in]

kinin

One of a family of POLYPEPTIDES, released as a part of the inflammatory process, which increase the leakiness of small blood vessels and cause smooth muscle fibres to contract.

kinin

the old name for CYTOKININ.

ki·nin

(kī'nin)
Polypeptide hormones released from diffuse stores and not from specialized tissue, rapidly inactivated at the site of release.
[G. kineō, to move, + -in]

kinin

(kī´nin),
n a number of widely differing substances having pronounced and dramatic physiologic effects. Some are formed in blood by proteolysis secondary to some pathologic process. Kinins stimulate visceral smooth muscle but relax vascular smooth muscle, thus producing vasodilation. May be involved in periodontal disease.

kinin

any of a group of endogenous peptides that increase vascular permeability, elevate blood pressure, and induce smooth muscle contraction.

venom kinin
a peptide found in the venom of insects.