veno-occlusive


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veno-occlusive

 [ve″no-ŏ-kloo´siv]
pertaining to or characterized by obstruction of the veins.
v.-o. disease of liver acute or chronic, partial or complete, occlusion of the branches of the hepatic veins by endophlebitis and thrombosis, leading to centrilobular necrosis, fibrosis, and ascites; most often seen in children.

veno-occlusive

(vē″nō-ŏ-kloo′sĭv)
Concerning obstruction of veins.

veno-occlusive

Causing veins to be closed by flattening or other means.

veno-occlusive

pertaining to or characterized by obstruction of the veins.

veno-occlusive disease of liver
acute or chronic, partial or complete, occlusion of the branches of the hepatic veins by endophlebitis and thrombosis, leading to centrilobular necrosis, fibrosis and ascites; occurs at a higher than normal prevalence in cheetahs and snow leopards.
References in periodicals archive ?
Pulmonary veno-occlusive disease: advances in clinical management and treatments.
Defibrotide for the Treatment of Severe Hepatic Veno-Occlusive Disease: An Analysis of Clinical Benefit As Determined By Number Needed to Treat (NNT) to Achieve Complete Response and to Improve Survival.
However, although the transmission of DENV was demonstrated, the patient's death was probably caused by hepatic veno-occlusive disease and toxic enterocolitis related to the conditioning regimen.
fatal veno-occlusive disease of the liver after chemotherapy, whole-body irradiation and bone marrow transplantation for refractory acute leukaemia.
Gentium recently filed a marketing authorization application with the European Medicines Agency (EMA) for the prevention and treatment of hepatic veno-occlusive disease (VOD) in adults and children undergoing stem-cell transplantation therapy.
Individualized therapeutic drug monitoring must be performed to ensure that busulfan concentrations are optimal for treatment and to reduce the risk for graft rejection, disease relapse, and sinusoidal obstruction syndrome (SOS), previously known as veno-occlusive disease.
The biopharmaceutical firm was testing the use of the drug, defibrotide, for preventing veno-occlusive disease (VOD) in pediatric patients who were at high risk.
Hepatic sinusoidal obstruction syndrome: a toxic injury to sinusoidal endothelial cells causing a cascade of events, including compromised blood flow to centrilobular hepatocytes, fibrosis, and obstruction of hepatic blood flow; also known as veno-occlusive disease of the liver
Although best known for their hepatotoxicity (where the bioactive metabolites, such as the dehydropyrrolic products, lead to veno-occlusive diseases and cirrhosis), activated PAs can elicit significant genotoxicity and can be carcinogenic as well as anticarcinogenic (which has led to their experimental use in chemotherapy).
A seventh patient was reported to have died 72 days after treatment of "regimen-related veno-occlusive disease of the liver.
Peak systolic blood flow improved in three (43%) of seven men with baseline hemodynamic impairment, and veno-occlusive disease resolved in three (18%) of 17 individuals.