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vasopeptidase inhibitor

   Also found in: Acronyms 0.01 sec.
vasopeptidase inhibitor
Cardiology An agent–eg, omapatrilat, that inhibits neural endopeptidase and angiotensin-converting enzyme, modulating cardiac function and bp in Pts with HTN. See Isolated systolic hypertension, Omapatrilat, OPERA.


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Omapatrilat is an investigational drug in a new class of cardiovascular medications, called vasopeptidase inhibitors (VPIs), which simultaneously inhibits two key enzymes that regulate heart function and blood pressure -- neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE).
9 BMS's vasopeptidase inhibitor Vanlev (omapatrilat) had demonstrated the greatest antihypertensive efficacy among novel compounds in recent years, giving rise to the development of several other potential members in this class.
It will accelerate the research of innovative cardiovascular molecules in our newly acquired research center, Bioprojet Biotech, and the clinical development of our vasopeptidase inhibitor," said Jeanne-Marie Lecomte, Ph.
 
 
 
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