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vasoactive intestinal polypeptide

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
polypeptide /poly·pep·tide/ (-pep´tīd) a peptide containing more than two amino acids linked by peptide bonds.
vasoactive intestinal polypeptide  a hormone that has vasoactive properties, stimulates intestinal secretion of water and electrolytes, inhibits gastric secretion, promotes glycogenolysis, causes hyperglycemia, and stimulates production of pancreatic juice.

vasoactive intestinal polypeptide
n. Abbr. VIP
A polypeptide hormone usually secreted by non-beta islet cell tumors of the pancreas, producing copious watery diarrhea and fecal electrolyte loss, resulting in hypokalemia.

vasoactive intestinal polypeptide (VIP),
a glucagon-secretin hormone found in the pancreas, intestine, and central nervous system. The hormone stimulates insulin and glucagon release. Gastric secretion, gastric motility, and peripheral vasodilation, as well as hyperglycemia by hepatic glycogenolysis, are inhibited. See also VIPoma.

polypeptide [pol″e-pep´tīd]
a peptide containing two or more amino acids linked by a peptide bond; called dipeptide, tripeptide, etc., depending on the number of amino acids present.
vasoactive intestinal polypeptide see vasoactive intestinal polypeptide.

vasoactive [vas″o-ak´tiv]
exerting an effect upon the caliber of blood vessels.
vasoactive intestinal polypeptide (VIP) a peptide hormone that, in addition to its vasoactive properties, stimulates intestinal secretion of water and electrolytes, inhibits gastric secretion, promotes glycogenesis, causes hyperglycemia, and stimulates production of pancreatic juice. See also vipoma.


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While the most common mediators of salivary gland secretion are autonomic, neurons release vasoactive intestinal polypeptide and substance P, thereby stimulating acinar cells to release calcium and secrete saliva.
Proposed factors in the pathogenesis of HPS include nitric oxide, prostaglandins, vasoactive intestinal polypeptide (VIP), calcitonin, tyrosine, serotonin, and endothelin.
Wiesel, 'Increase in retinal vasoactive intestinal polypeptide after eyelid fusion in primates', Proceedings of the National Academy of Sciences of the United States of America, vol.
 
 
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Vasoactive intestinal peptide
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vasoactive intestinal peptide (VIP), vasoactive intestinal polypeptide
vasoactive intestinal peptide (VIP), vasoactive intestinal polypeptide
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Vasoactive intestinal peptide receptor
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