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vascularization

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vascularization /vas·cu·lar·iza·tion/ (vas″ku-ler-ĭ-za´shun)
1. the process of becoming vascular.
3. the surgically induced development of vessels in a tissue.

vas·cu·lar·i·za·tion (vsky-lr--zshn)
n.
1. The formation of blood vessels.
2. An abnormal or pathological formation of blood vessels.

vascularization
[vas′kyəler′īzā′shən]
the process by which body tissue develops proliferating capillaries. It may be natural or induced by surgical techniques. vascularize, v.

vascularization
the formation of new blood vessels in tissues.

neovascularization
Development of new blood vessels, especially in tissues where circulation has been impaired by disease or trauma.
choroidal neovascularization (CNV) Abnormal growth of blood vessels, originating in the choriocapillaris, which pass through Bruch's membrane and then proliferate under the retinal pigment epithelium (type 1) and/or under the retina (type 2). It may occur as a result of a rupture of Bruch's membrane, release of cytokines (e.g. VEGF), inflammation, oxidative stress to the retinal pigment epithelium, or vascular insufficiency. The condition is the main cause of exudative (wet) age-related macular degeneration and it may be associated with various disorders including angioid streaks, choroidal rupture, pathological myopia, chorioretinal scars and birdshot retinochoroidopathy. See age-related macular degeneration.
corneal neovascularization See pannus.
iris neovascularization Abnormal formation of new blood vessels on the anterior surface of the iris. It is commonly associated with many conditions that have led to retinal ischaemia, such as diabetic retinopathy, occlusion of the central retinal vein, carotid arterial disease, uveal melanoma, long-standing retinal detachment, etc. The neovascularization begins at the pupil margin and often at the same time in the angle of the anterior chamber and spreads over the whole surface. New vessels are associated with fibrous tissue membranes, which may block the passage of aqueous humour through the trabecular meshwork (neovascular glaucoma) and ectropion uveae near the pupillary margin. Treatment typically includes photocoagulation to prevent the formation of new blood vessels.

pannus 
Abnormal superficial vascularization of the cornea covering the upper half, or sometimes the entire cornea. It is characterized by a thick plexus of vessels. It is found in some cases of contact lens wear, mainly soft lenses. Pannus following contact lens wear is referred to as corneal vascularization. If induced by soft lenses, it can be reduced by changing to lenses of high oxygen transmissibility or ceasing contact lens wear. Deep corneal vascularization involving the stroma is usually the result of a disease process (e.g. interstitial keratitis, phlyctenular keratitis, severe long-standing trichiasis, trachoma).


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