valproate


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Related to valproate: carbamazepine, Sodium valproate

valproate

 [val-pro´āt]
a salt of valproic acid with anticonvulsant activity similar to that of the acid.

valproate

/val·pro·ate/ (val-pro´āt) a salt of valproic acid; the sodium salt has the same uses as the acid.

valproate

(văl-prō′āt)
n.
A salt or ester of valproic acid, especially the sodium form, which is used as an anticonvulsant.

valproate

[val-pro′āt]
a salt of valproic acid with anticonvulsant activity similar to that of the acid.
References in periodicals archive ?
In June 2011, the FDA issued an alert when interim results of this study found that at age 3 years, children exposed to valproate had lower scores on cognitive tests, information that was added to the labels at that time.
Children of women who used valproate during pregnancy had a higher risk of autism spectrum disorder and childhood autism compared with children of women who did not use valproate," the researchers wrote.
The authors point out that other research has pointed to the potentially harmful effects of valproate on the developing fetus, and that the findings of the current study back other preliminary research.
In 2010, he received travel support from Sanofi-Aventis, a manufacturer of valproate.
The valproate binding sites on plasma proteins are easily saturable, however, and at plasma valproate concentrations modestly greater than the therapeutic maximum, the fraction of total valproate bound to protein starts to decrease.
Fetal valproate syndrome: is there a recognisable phenotype?
The new study is important because it's the largest to show a connection between valproate and diminished IQ.
The primary objective of the extension phase was to assess the long-term safety and tolerability of ABILIFY in combination with lithium or valproate.
His GP has tried lithium and valproate semi-sodium but he still has highs and lows and we are all suffering.
Depacon--sold as valproate by generic drugmakers Abraxis Pharma and Bedford--was best for those with generalized onset seizures and difficult to classify cases, the British researchers said.