valproate


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Related to valproate: carbamazepine, Sodium valproate

valproate

 [val-pro´āt]
a salt of valproic acid with anticonvulsant activity similar to that of the acid.

valproate

/val·pro·ate/ (val-pro´āt) a salt of valproic acid; the sodium salt has the same uses as the acid.

valproate

(văl-prō′āt)
n.
A salt or ester of valproic acid, especially the sodium form, which is used as an anticonvulsant.

valproate

[val-pro′āt]
a salt of valproic acid with anticonvulsant activity similar to that of the acid.
References in periodicals archive ?
Because valproate medicines are all licensed at national level, the PRAC recommendations will now be sent to Co-ordination Group for Mutual Recognition and Decentralised Procedures Human (CMDh), which will adopt a position.
As a Trust, we do not prescribe valproate to girls and women of childbearing potential aged 8 to 50 years old, or women who are pregnant.
The lithium and valproate mean doses were 1014 mg/day and 1250 mg/day, respectively, at the time of clinical and neuropsychological assessment.
2+] current in thalamus like sodium valproate or the drugs which possess gamma-aminobutyric acid ([GABA.
Of those who continued on LATUDA adjunctive therapy plus lithium or valproate in the longer-term study, at least 5% experienced parkinsonism, somnolence, akathisia, insomnia, anxiety, headache, and nausea.
There are few reports available that have described the association of valproate use with the appearance of NMS; however, in these cases, patients were also on antipsychotics.
The effect of valproate on body weight and hormones has been studied in 52 healthy adults who were randomized to valproate or placebo in a double-blind protocol [95].
In contrast, women on an enzyme-inhibiting drug, valproate, had the highest rate of increased seizures when starting a hormonal contraceptive, 29%.
Analyses in the prior Neurodevelopmental Effects of Antiepileptic Drugs (NEAD) study have shown that valproate is linked to major congenital malformations and lower IQ in toddlers (N.
In addition, according to the Naranjo ADR probability scale (2) used as an assessment tool, the adverse event was probably related to sodium valproate (six points).