valinomycin


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val·in·o·my·cin

(val'i-nō-mī'sin),
Cyclododecadepsipeptide ionophore antibiotic derived from Streptomyces fulvissius; used as an insecticide and nematocide.

valinomycin

ionophore consisting of a cyclic trimer of tetrapeptides. Specifically transports potassium ions across cell membranes. Inhibitor of oxidative phosphorylation due to its action in antagonizing the proton motive force.
References in periodicals archive ?
Cells were then washed twice in PBS, and the calibration curve samples were resuspended in valinomycin and nigericin with pH calibration buffers of pH 5.
79) Primary mouse HSCs were cultured in the presence or absence of two chemical uncouplers--carbonyl cyanide-p-trifluoromethoxyphenylhydrazone (FCCP) or valinomycin.
2008) determined another actinomycete peptide antibiotic, valinomycin isolated from Streptomyces sp.
Antifungal Activity of Valinomycin, a Peptide Antibiotic Produced by Streptomyces sp.
Interestingly, fibroblasts from patients showed a more rapid loss of their membrane potential after exposure to valinomycin compared to those from healthy donors.
Response of cochlear potentials to presumed alterations of ionic conductance: endolymphatic perfusion of barium, valinomycin and nystatin.
Potassium ion concentration on the LX20 is determined by indirect potentiometry, using an ISE with a valinomycin ionophore (1).
The mitochondrial toxin produced by Streptomyces griseus strains isolated from indoor environment is valinomycin.
The ISE chemistry uses an electrode containing a valinomycin membrane in conjunction with a reference electrode to determine potassium activity via indirect potentiometry.
To avoid interference from native ammonia in the sample, an additional ammonium ISE is used as well as a potassium ISE based on the ionophore valinomycin to compensate for interference from potassium ions at the ammonium sensors.