vacuolar myelopathy

myelopathy /my·elop·a·thy/ (mi″ĕ-lop´ah-the)

1. any functional disturbance and/or pathological change in the spinal cord; often used to denote nonspecific lesions, as opposed to myelitis.

2. pathological bone marrow changes.myelopath´ic

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carcinomatous myelopathy  rapidly progressive degeneration or necrosis of the spinal cord associated with a carcinoma.

chronic progressive myelopathy  gradually progressive spastic paraparesis associated with infection by human T-lymphotropic virus 1.

HTLV-1–associated myelopathy  chronic progressive m.

paracarcinomatous myelopathy , paraneoplastic myelopathy carcinomatous m.

spondylotic cervical myelopathy  that secondary to encroachment of cervical spondylosis upon a congenitally small cervical spinal canal.

transverse myelopathy  that extending across the spinal cord.

vacuolar myelopathy  loss of myelin and spongy degeneration of the spinal cord with microscopic vacuolization, caused by infection with human immunodeficiency virus.

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vacuolar myelopathy

Neurology A heterogeneous group of conditions characterized by spinal cord degeneration; VM occurs in up to 20% of AIDS Pts; it is most extensive in the lateral columns of the middle and lower thoracic segments. Cf Spongy degeneration.